Medical MCQ - Which of the following is true regarding the offspring of those with Huntington’s disease

Which of the following is true regarding the offspring of those with Huntington’s disease

Half of the offspring are at risk only if the affected parent is male

Half of the offspring are at risk only if the affected parent is female

Half of the offspring are at risk for the disease

Half of the offspring are at risk if either parent is symptomatic for the disease before age of 30

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Correct Answer:

Half of the offspring are at risk for the disease

Description:

As Huntington's disease is an autosomal dominant disease half of the offspring are affected . Age at which a patient becomes symptomatic is variable and has no effect on probability of transmitting the disease.

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