Which of the following is true regarding ideal alveolar ventilation- perfusion ratio?

Correct Answer: Maximum at apex of lung
Description: Ans. A. Maximum at apex of lunga. The ratio of pulmonary ventilation to pulmonary blood flow for the 'whole' lung at rest is about 0.8 (4.2 liter/minute ventilation divided by 5.5 liter/minute of blood flow).b. There are relatively marked differences in ventilation-perfusion ratio in various parts of the normal lung due to the effect of gravity, and local changes in the ventilation perfusion ratio are common in disease.c. Ventilation, as well as perfusion, in the upright position declines in a linear fashion from the bases to the apices of the lungs. However, the ventilation-perfusion ratios are high in the upper portions of the lungs.d. This high ventilation perfusion ratio at the apices account for the predilection for tuberculosis for this area of lung because the relatively high alveolar PO2 that results provides a favorable environment for the growth of tubercle bacilli
Category: Physiology
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