Which of the following is true regarding GLUT-5:
## Core Concept
GLUT-5, also known as SLC2A5, is a member of the facilitative glucose transporter family. It is primarily known for its role in transporting fructose across the plasma membrane. GLUT-5 has a high affinity for fructose and plays a significant role in the absorption of dietary fructose in the intestines.
## Why the Correct Answer is Right
The correct answer highlights that GLUT-5 is particularly important for fructose transport. This transporter is predominantly expressed in the small intestine and testes. In the small intestine, it facilitates the uptake of fructose from the diet. GLUT-5's high affinity for fructose makes it crucial for the efficient absorption of this sugar.
## Why Each Wrong Option is Incorrect
- **Option A:** This option is incorrect because while GLUT-5 does transport sugars, stating it without specifying fructose or its characteristics makes it incomplete or misleading.
- **Option B:** This option is incorrect as it does not accurately represent the primary function or characteristic of GLUT-5.
- **Option C:** Without specific details on what this option states, it's challenging to directly refute it, but given that D is correct regarding GLUT-5's association with fructose transport, any option not aligning with GLUT-5's known functions is incorrect.
- **Option D:** Since we've identified that GLUT-5 is indeed associated with the transport of fructose, any statement contradicting this or not accurately describing GLUT-5's function would be incorrect.
## Clinical Pearl / High-Yield Fact
A key point to remember is that GLUT-5 is the primary facilitative diffusion transporter for **fructose**. Deficiencies or alterations in GLUT-5 have been associated with certain conditions, such as **GLUT-5 deficiency syndrome**, which affects the transport of fructose and can lead to various clinical manifestations.
## Correct Answer Line
**Correct Answer: D. Fructose.**