Which of the following is true of psoriatic ahritis –
Correct Answer: All of the above
Description: Psoriatic ahritis refers to an inflammatory musculoskeletal disease that has both autoimmune and autoinflammatory features characteristically occurring in individuals with psoriasis. In 60-70% of cases, psoriasis precedes joint disease. In 15-20% of cases,the two manifestations appear within 1 year of each other. In about 15-20% of cases, the ahritis precedes the onset of psoriasis and canpresent a diagnostic challenge. The frequency in men and women is almost equal, although the frequency of disease patterns differs some what in the two sexes. The disease can begin in childhood or late in lifebut typically begins in the fouh or fifth decade, at an average age of 37 years. Many classification schemes have been proposed for the broad spectrum of ahropathy in PsA. Wright and Moll described five patterns: (1) ahritis of the DIP joints; (2) asymmetric oligoahritis; (3) symmetric polyahritis similar to RA; (4) axial involvement (spine and sacroiliac joints); and (5) ahritis mutilans, a highly destructive form of the disease. These patterns frequently coexist, and the pattern that persists chronically often differs from that of the initial presentation.A simpler scheme in recent use contains three patterns: oligoahritis,polyahritis, and axial ahritis. Ref - Harrisons 20e p2517
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