Medicine which of the following is the most potent stimulus for the devlopment of cor pulmonale in patients with chronic obstructive pulmonary disease? A obliteration of pulmonary vascular bed B alveolar membrane damage C left ventricular failure D hypoxia 💡 Explanation which of the following is the most potent stimulus for the devlopment of cor pulmonale in patients with chronic obstructive pulmonary disease? ✓ Correct Answer: D. hypoxia