Which of the following is the most likely effect of insulin at the cellular receptor level?
Correct Answer: stimulating tyrosine kinase
Description: Insulin binding to its receptor stimulates tyrosine kinase activity. Other stimulators of protein kinases include platelet-derived growth factor and epidermal growth factor. Tyrosine phosphorylation results from this interaction. Insulin-resistant states can be caused by pre-receptor resistance (mutated insulin, anti-insulin antibodies) or receptor and post receptor resistance.
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