Azithromycin for management of pneumococcal pneumonia Modality Regimen Previously healthy and no antibiotics in past 3 months: A macrolide or Doxycycline (100 mg PO BD) Comorbidities or antibiotics in past 3 months: select an alternative from a different class Fluoroquinolone or A b- lactam plus a macrolide In regions with a high rate of "high-level" pneumococcal macrolide resistance,consider alternatives listed above for patients with comorbidities