Placental steroid sufatase deficiency is an X-linked disorder (affects only males) that does not lead to ambiguous genitalia in a female child. 'Placental steroid suflatase deficiency is a rare X-linked disorder and all affected fetuses are males' William's 22nd/81 Congenital adrenal hyperplasia is the most common cause of ambiguous genitalia in female child. Fetal placental aromatase deficiency and WNT-4 gene mutation cause ambiguous genitalia in female child.