Which of the following is the earliest sign of ulcerative colitis on double-contrast barium enema study –

Correct Answer: Mucosal granularity
Description: Earliest radiological change of UC on barium enema is blurring of the mucosal lining and a fine granularity when mucosa is seen enface due to edema. Earliest radiological change of Crohn's disease → Aphthous lesions (Bull's eye or Target lesions).
Category: Radiology
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