Which of the following is the drug of choice for the treatment of syndrome of inappropriate Antidiuretic Harmone secretion?

Correct Answer: Demeclocycline
Description: SIADH is due to excessive secretion of anti-diuretic hormone. It is diametrically opposite disease to diabetes insipidus. Vasopressin, Thiazide and chloropropamide are used for the treatment of diabetes insipidus whereas demeclocycline is used for SIADH management.Now-a-days,vasopressin receptor antagonists like tolvapton and conivaptan are preferred for SIADH.
Category: Pharmacology
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