Which of the following is recombinant PTH ?
**Core Concept**
Recombinant PTH (Parathyroid Hormone) is a synthetic form of the hormone used in the treatment of osteoporosis and hypoparathyroidism. It works by stimulating bone growth and increasing calcium levels in the blood.
**Why the Correct Answer is Right**
Recombinant PTH, also known as teriparatide, is produced through genetic engineering and contains the same amino acid sequence as the natural hormone. It binds to the PTH receptor in bone, stimulating osteoblasts to produce new bone matrix and increasing bone mineral density. This leads to an increase in bone strength and a reduction in the risk of fractures. Teriparatide is administered subcutaneously once daily and is effective in treating osteoporosis in postmenopausal women and men.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it is not a recombinant form of parathyroid hormone.
**Option B:** This option is incorrect because it is a different type of medication used to treat osteoporosis, not a recombinant form of parathyroid hormone.
**Option C:** This option is incorrect because it is a different hormone used to treat hypercalcemia, not a recombinant form of parathyroid hormone.
**Clinical Pearl / High-Yield Fact**
Recombinant PTH is the only anabolic agent approved for the treatment of osteoporosis, meaning it promotes bone growth rather than just preventing bone loss. It is essential to note that recombinant PTH is not suitable for patients with hypercalcemia or those taking thiazide diuretics.
**Correct Answer: C. Teriparatide**