**Core Concept**
The question is testing the concept of organ specificity in pharmacology, which refers to the ability of a drug to target a specific organ or system in the body. Organ specificity is a desirable property of a drug, as it reduces the risk of side effects and improves its efficacy.
**Why the Correct Answer is Right**
Organ specificity is often achieved through the use of prodrugs, which are inactive compounds that require metabolic activation to become pharmacologically active. One example of an organ-specific prodrug is **Enalapril**, which is a prodrug of **Enalaprilat**. Enalapril is primarily metabolized by **angiotensin-converting enzyme (ACE)** in the **liver**, producing Enalaprilat, which is then excreted into the bloodstream and acts as an **ACE inhibitor** to lower blood pressure. The liver's role in metabolizing Enalapril makes it an organ-specific prodrug.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it does not provide a clear example of an organ-specific prodrug.
* **Option B:** This option is incorrect because it does not accurately describe the mechanism of action of the correct answer.
* **Option C:** This option is incorrect because it is not a specific example of an organ-specific prodrug.
**Clinical Pearl / High-Yield Fact**
When choosing a drug for a patient, it is essential to consider the concept of organ specificity to minimize side effects and maximize efficacy.
**Correct Answer:** C. Enalapril
Free Medical MCQs · NEET PG · USMLE · AIIMS
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