## Core Concept
A metopic suture is a type of **suture** that occurs in the **frontal bone** of the skull. It is a congenital condition where there is a failure of fusion of the two halves of the frontal bone during fetal development. This results in a persistent suture line in the forehead.

## Why the Correct Answer is Right
The correct answer states that a metopic suture is not associated with **increased risk of meningitis**. Metopic sutures are generally considered a benign anatomical variation. They are not typically associated with an increased risk of infections such as meningitis. The presence of a metopic suture does not usually have significant clinical implications.

## Why Each Wrong Option is Incorrect
* **Option A:** A metopic suture can be associated with **other cranial anomalies**, such as craniosynostosis or other skull abnormalities. Therefore, stating that it occurs in isolation is not entirely accurate.
* **Option B:** Metopic sutures are more commonly seen in **males** than in females, which makes this statement correct but does not directly relate to why the correct answer is right.
* **Option C:** The presence of a metopic suture can sometimes be associated with **developmental delay** or other neurodevelopmental issues, although this is not a hard and fast rule.

## Clinical Pearl / High-Yield Fact
A key point to remember is that metopic sutures are a relatively common anatomical variation, occurring in about **4-10%** of the population. They are usually of no clinical significance but can be important in the context of **trauma** or **cranial surgery**.

## Correct Answer: D.