Which of the following is not associated EBV virus ?
**Core Concept**
The Epstein-Barr virus (EBV) is a member of the herpesvirus family that is associated with various human diseases, particularly those of the lymphoid and epithelial systems. EBV is known to cause infectious mononucleosis, also known as glandular fever, and has been linked to several types of cancer, including Burkitt lymphoma and nasopharyngeal carcinoma.
**Why the Correct Answer is Right**
EBV is primarily associated with lymphoid malignancies such as Burkitt lymphoma, Hodgkin lymphoma, and post-transplant lymphoproliferative disorders. It is also linked to nasopharyngeal carcinoma, a type of cancer that affects the nasopharynx. Additionally, EBV is known to cause infectious mononucleosis, characterized by fever, sore throat, and lymphadenopathy.
**Why Each Wrong Option is Incorrect**
**Option A:** While EBV is primarily associated with lymphoid malignancies, it is not commonly linked to gastrointestinal carcinomas like gastric cancer. Gastric cancer is more often associated with H. pylori infection.
**Option B:** EBV is indeed associated with nasopharyngeal carcinoma, which is a type of head and neck cancer.
**Option C:** EBV is linked to post-transplant lymphoproliferative disorders, a complication that can occur in immunocompromised patients.
**Option D:** This option is not provided.
**Clinical Pearl / High-Yield Fact**
EBV is a ubiquitous virus that infects most people at some point in their lives, often without causing noticeable symptoms.
**Correct Answer: A. Gastric cancer**