**Core Concept:** Autosomal dominant disorders are genetic conditions where an allele (one of two genes) on an autosome (non-sex chromosome) determines the presence of the disorder. Inheritance occurs when an affected individual passes on the abnormal gene to one of their offspring with equal probability (50%) irrespective of the sex of the parent.
**Why the Correct Answer is Right:** Option C, "Hereditary Hemochromatosis," is not an autosomal dominant disorder because it is an autosomal recessive disease. In autosomal recessive disorders, both alleles must be abnormal for the disease to manifest. In contrast, autosomal dominant disorders only require one abnormal allele.
**Why Each Wrong Option is Incorrect:**
A. Hereditary Hemophilia: This is an autosomal recessive disorder, not an autosomal dominant disorder. In autosomal recessive disorders, both alleles must be abnormal for the disease to manifest.
B. Cystic Fibrosis: Cystic Fibrosis is also an autosomal recessive disorder, similar to Hereditary Hemophilia.
D. Gaucher Disease: Gaucher Disease is an autosomal recessive disorder, like Hereditary Hemophilia and Cystic Fibrosis.
**Clinical Pearl / High-Yield Fact**: Understanding inheritance patterns is crucial for diagnosing genetic disorders correctly. Autosomal dominant disorders are important to recognize because they can be inherited from either parent, and the penetrance (the probability of expressing the trait) is 100% for an affected individual.
**Correct Answer:** C. Hereditary Hemochromatosis
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.