Which of the following is not administered by intradermal route
**Core Concept**
Intradermal injections involve administering a substance into the dermal layer of the skin, typically for diagnostic or immunological purposes. This route is chosen for its ability to elicit a localized immune response or to administer allergens for skin testing.
**Why the Correct Answer is Right**
The correct answer is the substance that cannot be administered through the intradermal route due to its properties or intended use. Injections given intradermally should be clear, colorless, or have a minimal volume to avoid causing discomfort or necrosis. Substances that are too viscous or cause significant tissue reaction are generally not administered intradermally.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it's a substance that can be given intradermally for diagnostic purposes, like allergy testing.
**Option B:** This option is incorrect because it's a substance that can be given intradermally for immunological testing or as a vaccine adjuvant.
**Option C:** This option is incorrect because it's a substance that can be given intradermally for diagnostic purposes, such as allergy testing or skin prick testing.
**Clinical Pearl / High-Yield Fact**
Substances with high viscosity or those that cause significant tissue reaction should not be administered intradermally, as they can cause discomfort, necrosis, or other adverse effects.
**Correct Answer:** D