Which of the following is not a feature of malignant transformation by cultured cells?
Correct Answer: Increased requirement for growth factors
Description: When malignant transformation occur in cultured cells, their requirement for growth factors does not increase. On the contrary it decreases. The process of malignant transformation is associated with a stable, heritable loss of requirement of cultured cells for growth factors.Initial normal cell lines are fully dependent on growth factors and hormones for their growth. Once malignant transformation occurs, they become fully independent from hormones and growth factors. Ref: Robbins Pathologic Basis of Disease, 7th Edition, Pages 293-4; Harper Biochemistry, 26th Edition, Page 654
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now