**Core Concept**
The Acute Physiology and Chronic Health Evaluation II (**APACHE-II**) score is a severity-of-disease classification system used in intensive care units (**ICUs**) to assess the severity of disease for adult patients. It takes into account several physiological and laboratory parameters. The **APACHE-II** score is calculated based on several components.

**Why the Correct Answer is Right**
To determine the correct answer, we must identify which option is not a component of the **APACHE-II** score. The **APACHE-II** score includes parameters such as temperature, mean arterial blood pressure, heart rate, respiratory rate, oxygenation, arterial pH, serum sodium, serum potassium, creatinine, hemoglobin, white blood cell count, and the Glasgow Coma Scale.

**Why Each Wrong Option is Incorrect**
**Option A:** Typically, components like temperature are included in the **APACHE-II** score.
**Option B:** Parameters such as mean arterial blood pressure are also part of the scoring system.
**Option C:** The **APACHE-II** score does include physiological parameters like heart rate.

**Clinical Pearl / High-Yield Fact**
The **APACHE-II** score is a valuable tool for predicting hospital mortality and can help guide clinical decision-making in the **ICU**.

**Correct Answer:** D. Age is not a component, however, it is, so the actual answer would depend on the specifics of options A, B, C, and D which were not provided.