Which of the following is most likely to cause of non Megaloblastic macrocytic anemia
Correct Answer: Hypothyroidism
Description: Ref Harrison 19 th ed pg 640 marrow is usually hypercellular and the anemia is based on ineffective erythropoiesis. The cause is usually a deficiency of either cobalamin (vitamin B12) or folate, but megaloblas- tic anemia may occur because of genetic or acquired abnormalities that affect the metabolism of these vitamins or because of defects in DNA synthesis not related to cobalamin or folate .
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