Which of the following is most impoant molecule for antioxidant pathway in lens?
Correct Answer: Glutathione
Description: Glutathione is the most impoant molecule for antioxidant pathway in lens. Preventive antioxidant mechanisms of lens : Glutathione Superoxide dismutase Catalase Ascorbate (VIT-C) Alpha-tocopherol (VIT -E) Carotenoids ascorbate and alpha tocopherol Vitamins C and E function as water-soluble and lipid-soluble chain-breaking antioxidants, respectively, and protect lipids, proteins, and membranes from oxidative damage. Glutathione Maintains the Ascorbate and alpha-tocopherol in the lens in the reduced state The normal lens contains sulphydryl-containing reduced glutathione and ascorbic acid (vitamin C), both ofwhich decrease with age and in cataract. * Auto-oxidation and high concentration of reduced glutathione in the lens maintains the lens proteins in a reduced state and ensures the integrity of the cell membrane pump Ros= Reactive Oxygen Species Reference: - Comprehensive ophthalmology A K Khurana 6th edition page 181 Parsons' Diseases of the Eye 22nd Edition page -188
Category:
Ophthalmology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now