Which of the following is false regarding Naphthalene poisoning?
**Core Concept**
Naphthalene is a polycyclic aromatic hydrocarbon commonly found in mothballs. It acts as a toxicant by inducing oxidative stress and mitochondrial dysfunction in various organs, particularly the liver and kidneys.
**Why the Correct Answer is Right**
Naphthalene poisoning occurs mainly through inhalation of vapors or ingestion of contaminated products. The toxic effects are mediated by its metabolite, 1,2-naphthalenequinone, which accumulates in the liver and kidneys, causing cellular damage and necrosis. The characteristic symptoms of naphthalene poisoning include jaundice, hemolytic anemia, and renal failure. The use of naphthalene-containing products has been associated with an increased risk of liver and kidney damage.
**Why Each Wrong Option is Incorrect**
**Option A:** Naphthalene has been reported to cause hemolysis in newborns. This statement is true, as naphthalene exposure has been linked to hemolytic anemia in infants.
**Option B:** The mechanism of naphthalene toxicity involves the inhibition of mitochondrial electron transport chain. This statement is true, as naphthalene disrupts mitochondrial function, leading to cellular damage.
**Option C:** Naphthalene is a known hepatotoxin. This statement is true, as naphthalene has been shown to cause liver damage, including necrosis and fibrosis.
**Clinical Pearl / High-Yield Fact**
In cases of naphthalene poisoning, prompt treatment involves supportive care, including fluid resuscitation and dialysis, as well as the use of antioxidants to mitigate oxidative stress.
**Correct Answer: Not Provided**