Which of the following is false about Transfusion-Related Acute Lung Injury?

A. Develops within 24 hours

B. Mostly seen after sepsis and cardiac surgeries

C. It's a cause of non-cardiogenic pulmonary edema

D. Plasma is more likely to cause it than whole blood

Correct Answer: Develops within 24 hours

Description: Ans: A. Develops within 24 hours(Ref Harrison 19/e 138e-5, 18/e p1217)Transfusion-Related Acute Lung Injury (TRALI):MC cause of transfusion related fatalities.Cause:Usually results from transfusion of donor plasma.Risk factors:Smoking.Chronic alcohol useShockLiver surgery (transplantation).Symptoms development:During or within 6 hrs of transfusion.Develops symptoms of hypoxia (PaO2/FIO2 <300 mmHg).Non-cardiogenic pulmonary edema signs including bilateral interstitial infiltrates on chest X-ray.

Category: Medicine

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