**Core Concept**
Oxytocin antagonists are pharmacological agents that block the action of oxytocin, a hormone involved in uterine contraction during labor, milk letdown in lactation, and social bonding. Oxytocin exerts its effects by binding to oxytocin receptors in the uterus and mammary glands.
**Why the Correct Answer is Right**
Atosiban is a selective oxytocin receptor antagonist that competitively inhibits the binding of oxytocin to its receptors. By blocking oxytocin receptors, atosiban reduces uterine contractions and delays labor. This makes it a useful agent for managing preterm labor. Atosiban's mechanism of action is distinct from other tocolytic agents, such as beta-agonists and calcium channel blockers, which work through different pathways to relax the uterus.
**Why Each Wrong Option is Incorrect**
* **Option A:** Methylergometrine is an oxytocin agonist, not an antagonist. It stimulates uterine contractions by mimicking the action of oxytocin.
* **Option B:** Nifedipine is a calcium channel blocker that relaxes the uterus by reducing intracellular calcium levels, but it is not an oxytocin antagonist.
* **Option D:** Terbutaline is a beta-agonist that relaxes the uterus by stimulating beta-adrenergic receptors, but it is not an oxytocin antagonist.
**Clinical Pearl / High-Yield Fact**
Oxytocin antagonists like atosiban are useful in managing preterm labor, as they can delay delivery without causing significant side effects. However, their use is limited by their potential to increase the risk of fetal distress and other complications.
**Correct Answer:** C. Atosiban
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.