Which of the following is an indication for the use of folinic acid?
Correct Answer: Counteracting toxicity of high dose methotrexate therapy
Description: Prophylaxis of neural tube defects require treatment with folic acid. Methotrexate toxicity can be prevented by 5'-formyltetrahydrofolate (folinic acid). Pernicious anemia requires the therapy with vitamin B12. Anemia associated with chronic renal failure is treated with erythropoietin.
Category:
Pharmacology
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