Which of the following is a precancerous condition of cancer stomach?
Correct Answer: Chronic gastric atrophy
Description: Premalignant Conditions of gastric carcinoma Atrophic gastritis: Both type A (autoimmune pernicious anemia) and type B (associated with H. Pylori) atrophic gastritis are associated with increase risk for gastric cancer. Gastric Polyp: Gastric polyp are of 5 type - inflammatory, hamaomatous, heterotopic, hyperplastic and adenomatous. Of these two namely hyperplastic and adenomatous are associated with increased risk for gastric carcinoma. Adenomatous polyp is having a risk of approximately 38% of malignant transformation and hyperplastic polyp have only Intestinal metaplasia and dysplasia: Both are precursor lesion of gastric cancer. Familial adenomatous polyposis coli: patients with familial adenomatous polyposis have a high prevalence of gastric adenomatous polyp (50%) and 10 times more likely to develop adenocarcinoma stomach. Ref: Schwaz 9/e, Page 927; Maingot's 10/e, Page 1006.
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