Which of the following is a marker for Down’s Syndrome?
Correct Answer: Decresed maternal serum alpha feto protein
Description: Ans. is 'b' i.e., Decresed maternal serum alpha feto protein Antenatal Screening for Downs syndromeo Following methods are used :-1) Triple test: It includesi) Unconjugated estrogen (estriol): decreased;ii) Maternal serum alpha- feto protein (MSAFP): decreased; andiii) hCG: increased(Note: All these three markers are decreased in Edward syndrome)2) New markers: These are (i) Increased inhibin A in maternal blood; and (ii) Decreased PAPA (pregnancy associated plasma protein).3) USG: It shows: (i) Increased nuchal translucency (increased nuchal fold thickness) in first trimester; (ii) Ductus venous flow reversed; and (iii) Nasal bone hypoplasia.4) Karyotyping: It can be done by chorionic villus sampling at 10-12 weeks or aminocentesis at 16-18 weeks.
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now