Which of the following is a common side effect of cisplatin ?
**Core Concept**
The question tests knowledge of **chemotherapy side effects**, specifically those related to **cisplatin**, a widely used **antineoplastic agent**. Cisplatin works by forming **platinum-DNA adducts** that interfere with DNA repair, leading to cell death.
**Why the Correct Answer is Right**
Although the correct answer choice is missing, a common side effect of cisplatin is **nephrotoxicity**, which can lead to **acute kidney injury**. This occurs due to the accumulation of cisplatin in renal cells, causing damage to the **renal tubules**. Another common side effect is **ototoxicity**, resulting in **hearing loss**.
**Why Each Wrong Option is Incorrect**
**Option A:** Without the specific option text, it's challenging to provide a detailed explanation.
**Option B:** Similarly, without the text, the reasoning cannot be accurately provided.
**Option C:** And **Option D:** require the actual text to assess their correctness.
**Clinical Pearl / High-Yield Fact**
A crucial point to remember is that **hydration** is key in preventing cisplatin-induced nephrotoxicity, as it helps to reduce the concentration of cisplatin in the kidneys.
**Correct Answer:** Unfortunately, the answer choices are not provided to give a specific correct answer.