**Carbonic Anhydrase Inhibitors**
**Core Concept**
Carbonic anhydrase inhibitors are a class of medications that block the action of carbonic anhydrase enzymes, which catalyze the reversible reaction of carbon dioxide to bicarbonate and protons. This reaction is crucial in various physiological processes, including respiration, electrolyte balance, and acid-base homeostasis.
**Why the Correct Answer is Right**
The correct answer is an oral medication that is primarily used in the treatment of glaucoma, epilepsy, and altitude sickness. It works by inhibiting carbonic anhydrase in the eye, thereby reducing intraocular pressure, and in the brain, which helps to reduce seizures. By inhibiting carbonic anhydrase, this medication decreases the reabsorption of bicarbonate in the proximal convoluted tubule, leading to increased urine production and reduced sodium and chloride reabsorption.
**Why Each Wrong Option is Incorrect**
**Option A:** This medication is a selective Ξ²2 adrenergic receptor agonist, not a carbonic anhydrase inhibitor.
**Option B:** This medication is a non-selective Ξ²-blocker, used primarily in the management of hypertension and angina.
**Option C:** This medication is a diuretic that acts by inhibiting sodium reabsorption in the distal convoluted tubule, but it is not a carbonic anhydrase inhibitor.
**Clinical Pearl / High-Yield Fact**
Carbonic anhydrase inhibitors can cause metabolic acidosis, hypokalemia, and increased risk of kidney stones due to the increased excretion of bicarbonate and sodium.
**Correct Answer:** C. Acetazolamide.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.