Ans. a. KetamineKetamine should be avoided in patients with history of seizures as it fuher increases ICP and also causes delirium and hallucinations. Contraindications of Ketamine:Head injury, intracranial space occupying lesion, eye injuryQ (increases ICT, IOT)Ischemic hea disease, vascular aneurysm and hypeensionQ (increases myocardial oxygen demand and hypeension)Psychiatric diseases and drug addictsdeg (more incidence of hallucination and emergence reaction)