Which of the following inhalational agent should not be used in closed circuit?
Correct Answer: Sevoflurance
Description: Sevoflurane, Trilene & Methoxyflurane are avoided in closed circuit.
Sevoflurane reacts with sodalime to produce compound A which is nephrotoxic.
Trilene reacts with sodalime and produces phosgene gas and dichloroacetylene which can cause ARDS & seizures respectively.
Methoxyflurane can react with rubber tubing of closed circuit.
Category:
Pharmacology
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