Which of the following has both endocrine and exocrine functions?
Correct Answer: Pancreas
Description: Ans: a (Pancreas)Pancreas has both exocrine and endocrine functions.There are 4 distinct types of pancreatic cells in human.A cells (alpha) - GlucagonB cells (beta) - InsulinD cells (delta) - SomatostatinF cells - Pancreatic polypeptide D1 cells - VIPEndocrine pancreas secretes hormones -glucagon, insulin and somatosta-tin. Exocrine pancreas secretes digestive enzymes like trypsin, chymot-rypsin.Site and mechanism of hormone action:-Mechanism and siteHormoneAt nuclear receptorThyroid ormonesAt cytoplasmic receptorsSteroidal hormones eg:- Glucocorticoids, Mineralocortyicoids, Estrogen, Progestins.At cytoplasmic receptorsa) Direct transmembrane activation of tyrosine protein kinase -InsulinPhosphorylation cascade b) Through IP3/DAG generationVasopressin, oxytocinc) Through alteration of intracellular cAMP concentration - alteration of protein kinase A activityAdrenaline, glucagon, TSH,LH, FSH, PTHACTH, Calcitonin
Category:
Physiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now