Which of the following glycosaminoglycans does not contain Uronic acid?
Correct Answer: Keratan Sulfate
Description: Keratan sulfate: Seen in costal cailages, cornea, nucleus pulposus and wall of the aoaComp: No URONIC ACIDHyaluronic acid: Sulphate free, not covalently bound to protein, seen in bacteriasForms the ground substance of connective tissue; Seen in the vitreous humor of eye and synol fluidComp: N-acetyl glucosamine + glucuronic acidDermatan sulfate: N-acetyl galactosamine + L-iduronic acidWeak anticoagulant propey. Also called b-heparinHeparin: Anticoagulant and lipid clearing agent. synthesis in the liver. Produced by mast cells(note-intracellular GAG)Also found in lungs, thymus, spleen, skin. A-glycosidic linkages seenComp: GlcN + glcUA/IDUA(5-epimerase conves GlcUA to IDUA)NH2 at C2, OH at C6, GlcUA, and IDUA are sulfatedIt occurs in combination with proteins(serine and gly) (proteoglycans) Harpers Biochemistry; 30th edition
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now