Medical MCQ-Which of the following drugs is to be immediately stopped in a patient of diabetes with HTN and serum creatinine level of 5.6 mg?

Which of the following drugs is to be immediately stopped in a patient of diabetes with HTN and serum creatinine level of 5.6 mg?

Metformin

Insulin

Metoprolol

Linagliptin

Question Category:

Pharmacology

Correct Answer:

Metformin

Description:

ANS. AMetformin is contraindicated in patients with high creatinine because of the risk of lactic acidosis.# Specific side effects of OHAMetformin1. GI symptoms2. B12 deficiency3. Lactic acidosis (especially in patients with high creatinine, liver failure, alcoholism, cardiorespiratory insufficiency)Piogiitazone1. Unsafe in Renal failure, Liver failure, cardiac failure2. Increased risk of bladder cancer3. OsteoporosisDPP-4 inhibitors1. Upper respiratory tract infection2. Renal toxicity (Vildagliptin is hepatotoxic)(Safest DPP-4 inhibitor in renal failure is linagliptan)(asked in Nov AIIMS 2016 and May 2017)SGLT2 inhibitors1. UTI2. Risk of bladder cancer

Previous MCQ

Next MCQ

Get More

Subject Mock Tests

Try practicing mock tests with over 200,000 questions from various medical subjects.

Attempt a mock test now

Mock Exam

Attempt an exam of 100 questions randomly chosen from all subjects.

Coming Soon