Medical MCQ-Which of the following drugs is hydrolyzed by a plasma esterase that is abnormally low in activity in about 1 in every 2500 humans?

Which of the following drugs is hydrolyzed by a plasma esterase that is abnormally low in activity in about 1 in every 2500 humans?

Ethanol

Rifampicin

Cimetidine

Succinylcholine

Question Category:

Pharmacology

Correct Answer:

Succinylcholine

Description:

* SCh is the shoest acting muscle relaxant due to its metabolism by pseudocholinesterase. * Some patients contain an atypical pseudocholinesterase (which has abnormally low activity) and are susceptible to develop apnea with the use of this drug.

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