Which of the following drugs can result in cyanide poisoning?
Correct Answer: Sodium Nitroprusside
Description: Rapid high dose infusion of sodium nitroprusside may result in cyanide poisoning. Mechanism of action of Sodium nitroprusside is binding with oxyhemoglobin in the circulation and release nitric oxide, cyanide, methaemoglobin results inincrease of cGMP Amyl nitrite induces methemoglobinemia which binds cyanide to form cyanmethemoglobin and thiosulphate hastens its conversion to less toxic thiocyanate. Amyl nitrite and sodium thiosulphate are present in commercial cyanide antidote kit. Hydroxocobalamin conves cyanide to non-toxic cyanocobalamin. Note Sodium nitroprusside- DOC for Malignant hypeension
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now