**Core Concept**
Goitrogens are substances that can interfere with thyroid hormone production by inhibiting the enzyme thyroid peroxidase (TPO), which is essential for the synthesis of thyroid hormones. This can lead to hypothyroidism or thyroid dysfunction.
**Why the Correct Answer is Right**
The correct answer is a drug that contains a sulfhydryl group (-SH), which can donate electrons to oxidize the TPO enzyme, thereby inhibiting thyroid hormone production. Examples of such compounds include certain amino acids like methimazole and propylthiouracil, which are used in the treatment of hyperthyroidism. However, in this context, we're looking for a drug that can act as a goitrogen, meaning it can interfere with thyroid function at higher doses or in susceptible individuals.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not a goitrogen and does not contain a sulfhydryl group. It's possible that this option is a drug used for a different indication.
* **Option B:** This option is not a goitrogen and does not have a known mechanism of action that would interfere with thyroid hormone production.
* **Option C:** This option is not a goitrogen and does not contain a sulfhydryl group. It's possible that this option is a drug used for a different indication.
**Clinical Pearl / High-Yield Fact**
Some medications, such as certain antithyroid drugs, can interfere with thyroid hormone production and lead to hypothyroidism. It's essential to monitor thyroid function tests in patients taking these medications, especially at higher doses.
**Correct Answer:** C.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.