Which of the following drug produce neutrophilia?
**Core Concept**
Neutrophilia is an increase in the number of neutrophils in the blood, often in response to infection or inflammation. This condition can be caused by various factors, including the administration of certain medications.
**Why the Correct Answer is Right**
The correct answer is a glucocorticoid, which is a class of steroid hormones that have anti-inflammatory properties. Glucocorticoids, such as prednisone, work by inducing the release of neutrophils from the bone marrow and reducing the rate of neutrophil apoptosis (programmed cell death). This leads to an increase in neutrophil count in the blood.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is likely a vaccine, which can stimulate an immune response but does not typically cause neutrophilia.
**Option B:** This option is likely a medication that suppresses the immune system, such as an immunosuppressant. Immunosuppressants would more likely cause neutropenia (a decrease in neutrophil count) rather than neutrophilia.
**Option C:** This option is likely an antibiotic, which targets bacteria and may cause a decrease in neutrophil count due to its effect on bacterial infections.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that glucocorticoids can cause neutrophilia, but they can also have other effects on the immune system, such as suppressing the lymphocyte response. This can make them useful in treating conditions like asthma, but also increases the risk of infections.
**Correct Answer:** C. Prednisone.