Which of the following drug is associated with highest cardiac moality?
Correct Answer: Rofecoxib
Description: Rofecoxib is a selective COX-2 inhibitor that was withdrawn due to increased risk of MI. ARBs (losaan) and b blockers (metoprolol) are cardioprotective in CHF. These decrease the moality. Nicorandil is a K+ channel opener used in angina. It is cardioprotective by causing ischemic pre-conditioning.
Category:
Pharmacology
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