Medical MCQ-Which of the following drug is a 5HT2c agonist approved for treatment of obesity and causes Serotonin Syndrome as an adverse effect?

Which of the following drug is a 5HT2c agonist approved for treatment of obesity and causes Serotonin Syndrome as an adverse effect?

Lorcaserin

Sibutramine

Modafinil

Rimonabant

Question Category:

Pharmacology

Correct Answer:

Lorcaserin

Description:

Lorcaserin: 5HT2c agonist Causes weight loss S/E: Serotonin syndrome Sibutramine: Serotonin and nor-adrenaline reuptake inhibitor Discontinued due to increased risk of stroke Modafinil: used in treatment of Narcolepsy Rimonabant: Inverse agonist of cannabinoid receptor - 1 Causes weight loss Prevents craving of alcohol S/E: psychological problems (withdrawn)

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