Which of the following drug does not cross the blood-placental barrier?
Correct Answer: Glycopyrolate
Description: Ref:KD Tripathi pharmacology 7th edition (page.no: 19,116) Placental membranes are lipoidal and allow free passage of lipophilic drugs while restricting hydrophilic drugs. Glycopyrrolate is a quaternary ammonium compound. So it can't cross placenta and brain(BBB). Other drugs can cross the placenta
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Pharmacology
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