Which of the following does not cross the blood-brain barrier?
Correct Answer: Pralidoxime
Description: Ref: KD Tripathi pharmacology 7th edition (page.no: 111) Katzung 11/e p121 Pralidoxime has positively charged quaternary nitrogen. Quaernary molecules are heavy and can't penetrate the blood-brain barrier Pralidoxime or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to treat organophosphate poisoning in conjunction with atropine and diazepam
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now