Physiology Which of the following changes occurs in RBCs of stored blood? A Increase in Na+ & K+ content B Decrease in Na+ & K+ content C Increase in Na+ & decrease in K+ content D Increased activity of Na+ - K+ ATPase. 💡 Explanation Which of the following changes occurs in RBCs of stored blood? ✓ Correct Answer: C. Increase in Na+ & decrease in K+ content