**Core Concept**
Lupus-like features are a collection of autoimmune manifestations that mimic systemic lupus erythematosus (SLE). This condition is characterized by the presence of antinuclear antibodies (ANA) and the involvement of multiple organs, including the skin, joints, kidneys, and central nervous system.

**Why the Correct Answer is Right**
The correct answer is a drug that is known to cause lupus-like reactions as a side effect. **Hydroxychloroquine** is a well-documented cause of drug-induced lupus, which is characterized by the presence of ANA and the involvement of multiple organs. The exact mechanism of drug-induced lupus is not fully understood, but it is thought to involve the binding of the drug to nuclear proteins, leading to the activation of immune cells and the production of ANA.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it is a medication that is used to treat autoimmune disorders, not cause lupus-like features.
* **Option B:** This option is incorrect because it is a medication that is used to treat infections, not cause lupus-like reactions.
* **Option C:** This option is incorrect because it is a medication that is used to treat cancer, not cause lupus-like features.

**Clinical Pearl / High-Yield Fact**
Drug-induced lupus is a rare but serious side effect of certain medications, including hydroxychloroquine. It is essential to monitor patients taking these medications for signs of lupus-like reactions, such as joint pain, skin rash, and kidney disease.

**Correct Answer: C. Hydroxychloroquine**