Which of the following can be used as a diagnostic modality for herpes labialis
Correct Answer: PCR assay
Description: PCR finds the genetic material (DNA) of the HSV virus. This test can tell the difference between HSV-1 and HSV-2. Using the PCR test on skin sores isn't common. PCR is used mainly for testing spinal fluid in rare cases when herpes may have caused an infection in or around the brain. Antibody tests. Serologic tests are often used to detect HSV because they can differentiate between HSV-1 and HSV-2. There is an FDA-approved point-of-care test called POCkit that gives results from capillary blood or serum during an office visit. These tests are 80% to 98% sensitive and more than 96% specific. Ref Harrison20th edition pg ,977
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