Which of the following best describes the drug phenomenon at pKa=pH?
Correct Answer: Drug exists as 50% ionized and 50% unionized
Description: pka is numerically equal to the pH at which a drug is 50% ionized. The pKa of a drug is the hydrogen ion concentration (pH) at which 50% of the drug exists in its ionized hydrophilic form (i.e., in equilibrium with its un-ionized lipophilic form) pKa is a different term than pH pH is simply a measure of the concentration in a given solution pKa is defined as the pH were a drug exists as 50% ionized and 50% unionized If pKa-pH = 0, then 50% of drug is ionized and 50% is unionized Ref: KDT 7th edition Pgno: 11,12
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now