Which of the following antipsychotic has Akathisia as its side effect?
Correct Answer: Haloperidol
Description: Akathisia is a term coined by Haskovec in 1904 to describe an inner feeling of restlessness, an inability to sit still, and a compulsion to move about. When sitting, the patient constantly shifts his body and legs, crosses and uncrosses his legs, and swings the free leg. Running in place and persistent pacing are also characteristic. This abnormality of movement is most prominent in the lower extremities and may not be accompanied, at least in mild forms of akathisia, by perceptible rigidity or other neurologic abnormalities. First noted in patients with Parkinson disease and senile dementia, akathisia is now observed most often in patients receiving neuroleptic drugs. This disorder can be induced in normal individuals by the administration of neuroleptic drugs or L-dopa. Akathisia refers to somatic restlessness which occur in patients treated with first generation antipsychotics. Among the options given haloperidol is an old generation antipsychotic which causes a side effect of akathisia. Drugs commonly used to treat akathisia are propranolol, benzodiazepines and anticholinergics. Ref: Ropper A.H., Samuels M.A. (2009). Chapter 6. Tremor, Myoclonus, Focal Dystonias, and Tics. In A.H. Ropper, M.A. Samuels (Eds), Adams and Victor's Principles of Neurology, 9e.
Category:
Psychiatry
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