Which of the following antimicrobial is effective against an organism producing extended spectrum beta lactamase?
Correct Answer: Piperacillin-Tazobactam
Description: Ans. (C) Piperacillin-tazobactam(Ref: Harrison 18th/1247)Organisms producing ESBL-like Klebsiella are resistant to most beta-lactams except carbapenems.ESBL can be inhibited by beta lactamase inhibitors.Amoxicillin is not effective against Klebsiella whereas piperacillin has wide spectrum including Klesiella.
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Pharmacology
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