Which of the following antiarrhythmic drugs can decrease the slope of Phase 0 and prolong the action potential duration?
Correct Answer: Quinidine
Description: Na+ channel blockers reduce the slope of phase 0 whereas K+ channel blockers prolong the APD. Both of these propeies are present in class Ia antiarrhythmics like quinidine and procainamide.
Category:
Pharmacology
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