Which of the following anaesthetic agent leads to increase in ICT
Correct Answer: Ketamine
Description: (Ref: Katzung, 11th ed. pg. 437; KDT, 6th ed. pg. 376)* Ketamine is the only intravenous anesthetic that possesses analgesic properties and produces cardiovascular stimulation.* It causes "dissociative anesthesia" which is characterized by profound analgesia, immobility, amnesia and feeling of dissociation from ones' own body and the surrounding.* It has bronchodilator effect therefore considered as Induction agent of choice in asthma patient.* In addition, it also causes:# Hallucination# Delusion and illusion# Profound analgesia* Ketamine increases all pressures like:# BP (hypertension), Heart rate, Cardiac output# Intracranial tension (it increases cerebral blood flow)# Intraocular pressure (IOP)* It is contraindicated in intracerebral mass/haemorrhage, MI, schizophrenia, EpilepsyMOA of Ketamine:* It acts by blocking NMDA receptor (of glutamate).Side effect of other given options:* Propofol: Apnea, Decreases BP and HR* Thiopentone: Laryngospasm, Shivering & Delirium* Etomidate: Adrenocortical suppression
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now