Which of the following agents used in hypeension is a prodrug that is conveed to its active form in the brain?
Correct Answer: Methyldopa
Description: Methyldopa (L-a-methyl-3,4-dihydroxyphenylalanine) is an analog of L-dopa. Methyldopa enters the brain an aromatic amino acid transpoer and is conveed to a-methyldopamine and a-methylnorepinephrine. Antihypeensive action appears to be due to stimulation of central a adrenoceptors by a-methylnorepinephrine or a-methyldopamine.Katzung Pharmacology 12th edition Pg: 175
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now